中国中西医结合杂志2018，Vol.38Issue(1)：15-19,5.DOI:10.7661/j.cjim.20171207.452
清肠温中方治疗轻中度溃疡性结肠炎的临床研究
Therapeutic Analysis of Qingchang Wenzhong Formula for Treatment of Mild-Moderate Ulcerative Colitis Patients
摘要
Abstract
Objective To observe the effects of Qingchang Wenzhong Formula (QWF) on mildmoderate ulcerative colitis (UC) patients with cold-heat jumble and stagnation of damp-heat syndrome (CDJSDHS).Methods Totally 72 mild-moderate UC patients were assigned to the treatment group and the control group according to random number table,36 cases in each group.Patients in the treatment group took QWF and mesalazine mimetics,while patients in the control group took mesalazine and QWF mimetics.The treatment course for all was 8 weeks.Before and after treatment scores of single symptom,Baron,improved Mayo score were used to evaluate therapeutic effects.Clinical symptoms of traditional Chinese medicine (TCM) were observed to evaluate TCM clinical efficacy.Inflammatory Bowel Disease Questionnaire (IBD-Q) was also used to judge life quality of the treatments.Results Sixty-one cases were enrolled by eliminating unqualified cases (29 cases in treatment group and 32 cases in control group).Compared with before treatment in the same group,scores of single symptom (abdominal pain,diarrhea,pus and blood stool),integral of TCM,Baron,improved Mayo score and IBD-Q in the treatment group were improved in the two groups after treatment (P ＜0.01).All indices showed no difference between two groups after treatment (P ＞ 0.05).Conclusion QWF could effectively ameliorate clinical symptoms and reduce disease activity,and improve life quality of mild-moderate UC patients in clinics.关键词
溃疡性结肠炎/随机对照/双盲/双模拟/清肠温中方Key words
ulcerative colitis/randomized control/double-blinded/double simulated/Qingchang Wenzhong Formula引用本文复制引用
王志斌,陈晨,郭一,石磊,孙中美,毛堂友,陈晓伟,李军祥..清肠温中方治疗轻中度溃疡性结肠炎的临床研究[J].中国中西医结合杂志,2018,38(1):15-19,5.基金项目
北京市首都特色临床应用研究项目(No.Z151100004015097) （No.Z151100004015097）
北京市科委“十病十药”项目(No.Z151100003815011) （No.Z151100003815011）
