中药材2017，Vol.40Issue(8)：1842-1845,4.DOI:10.13863/j.issn1001-4454.2017.08.020
牛膝化学成分研究
Chemical Constituents from Achyranthis Bidentatae Radix
摘要
Abstract
Objective:To studv the chemical constitutes from the Achyranthis Bidentatae Radix.Methods:The Achyranthis Bidentatae Radix were cut into pieces,and then extracted with 95％ ethanol.The concentrated extracting solution was separated and purified by semipreparative HPLC,Sephadex LH-20,and silica gel column chromatography.Their structures were elucidated on the basis of spectral data and physiochemical properties.Results:Thirteen compounds were isolated.They were identified as3-ecdysterone (1),25-R-inokosterone(2),25-S-inokosterone (3),polypodine B (4),turkesterone (5),palythoalone B (6),uracil glucoside (7),methyl pyroglutamic acid (8),adenine (9),pedatisectine D (10),N-trans-feruloyhyramine (11),N-cis-feruloyltyramine (12),N-trans-feruloyl-3-methoxytyramine-4'-O-β-D-glucopyranoside(13).Conclusion:Compounds 5 ～ 10 are isolated from this plant for the first time.关键词
牛膝/化学成分/土克甾酮/Palythoalone BKey words
Achyranthis Bidentatae radix/Chemical constituents/Turkesterone/Palythoalone B分类
医药卫生引用本文复制引用
赵会丽,王彦志,张磊,胡慧玲..牛膝化学成分研究[J].中药材,2017,40(8):1842-1845,4.基金项目
河南中医药大学科技创新团队、科技创新人才计划资助项目(2015XCXTD02) （2015XCXTD02）
河南中医学院省属高校基本科研业务专项支持计划(2014KYYWF-ZZCXZ-01) （2014KYYWF-ZZCXZ-01）
