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花脸香蘑子实体的甾醇类化合物

张正曦 隋先进 武海波 王文蜀 黄安民 高杉杉

中药材2017,Vol.40Issue(8):1849-1852,4.
中药材2017,Vol.40Issue(8):1849-1852,4.DOI:10.13863/j.issn1001-4454.2017.08.022

花脸香蘑子实体的甾醇类化合物

Steroids from Fruiting Bodies of Lepista sordida

张正曦 1隋先进 1武海波 1王文蜀 2黄安民 1高杉杉2

作者信息

  • 1. 中央民族大学生命与环境科学学院,北京100081
  • 2. 北京市食品环境与健康工程技术研究中心,北京100081
  • 折叠

摘要

Abstract

Objective:To study the constituents from fruiting bodies of Lepista sordida.Methods:The chemical constituents were isolated and purified by means of chromatographic techniques and their structures were elucidated by spectroscopic methods.Results:Ten steroids were isolated from the chloroform part of the ethanol extracts from Lepista sordida fruiting bodies,and identified as (22E,24R)-5α,8α-epidioxy-24-methy1-cholesta-6,9 (11),22-triene-3β-ol (1),5α,8α-epidioxy-24 (S)-methylergostane-6,9 (11)-dien-3β-ol (2),5 α,8α-epidioxy-(22E,24R)-ergosta-6,22-dien-3β-ol (3),(22E,24R)-ergosta-7,9 (11),22-triene-3β,5α,6β-triol (4),(20S,22E,24R)-ergosta-7,22-dien-3β,5 α,6β,9α-tetraol (5),(22E,24R)-ergosta-7,22-dien-3β,5 α,6β-triol (6),(22E,24R)-5 α,6α-expoxyergosta-8 (14),22-diene-3β,7α-diol (7),β-ergosterol (8),stigmasterol (9) andβ-sitosterol (10).Conclusion:All the compounds are isolated from Lepista sordida for the first time.

关键词

花脸香蘑/甾醇

Key words

Lepista sordida (Schum.: Fr.) Sing./Steroids

分类

医药卫生

引用本文复制引用

张正曦,隋先进,武海波,王文蜀,黄安民,高杉杉..花脸香蘑子实体的甾醇类化合物[J].中药材,2017,40(8):1849-1852,4.

基金项目

国家自然科学基金(31200260,31670564) (31200260,31670564)

建设世界一流大学(学科)和特色发展引导专项资金(YDZXXK201618) (学科)

中央高校基本科研专项基金(2016shxy07) (2016shxy07)

中央民族大学大学生创新训练计划资助项目(GCCX2016110029,URTP2016110044) (GCCX2016110029,URTP2016110044)

中药材

OA北大核心CSTPCD

1001-4454

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