中国现代中药2017，Vol.19Issue(10)：1371-1375,5.DOI:10.13313/j.issn.1673-4890.2017.10.004
博落回鲜叶中生物碱类化学成分的分离与结构鉴定
Isolation and Identification of Alkaloids from Fresh Leaves of Macleaya cordata
摘要
Abstract
Objective:To study the alkaloids from the leaf of Macleaya cordata.Methods:The alkaloids were isolated and purified by silica gel column chromatography and preparative liquid chromatography,and the structures were elucidated based on the spectral data.Results:14 alkaloids were obtained from the fraction of ethanol extract and identified as protopine (1),allocryptopine (2),sangunarine (3),chelerythrine (4),Norcheleryth-rine (5),dehydrocorydaline (6),N-meth yltetrahydrocoptisine (7),phellodendrine (8),6-methoxyldemethylsanguin-arine (9),6-cyanodihydrosangunarine (10),6-cyanodihydrochelerythrine (11),6-acetonyldihydrosangunarine (12),dihydrosangunarine (13) and dihydrochelerythrine (14).Conclusion:Compounds 5-9 are isolated from Macleaya cordata for the first time.关键词
博落回/叶/生物碱Key words
Macleaya cordata (Willd) R.Br./leaf/alkaloids引用本文复制引用
杨鹏,向锋,卿志星,曹华亮,曾建国..博落回鲜叶中生物碱类化学成分的分离与结构鉴定[J].中国现代中药,2017,19(10):1371-1375,5.基金项目
湖南省科技重点计划(2016SK3002) （2016SK3002）
