中国现代中药2017，Vol.19Issue(10)：1500-1504,5.DOI:10.13313/j.issn.1673-4890.2017.10.029
博落回中苄基异喹啉类生物碱生物合成与代谢工程研究概况
Overviews in Biosynthesis of Macleaya cordata Secondary Metabolites and Metabolic Engineering
摘要
Abstract
Plant growth produces a wide variety of secondary metabolites,many of which have very important medicinal value.However,the content of secondary metabolites with significant medicinal value are low in plants,while the use of microbial metabolic engineering technology can provide a new source of secondary metabolites pathway.In this paper,we reviewed the biosynthesis of plant secondary metabolites,especially the benzylisoquinoline alkaloids of Macleaya spp.,as well as the research progress of heterologous expression and production of benzylisoquinoline alkaloids in yeast using microbial metabolic engineering technology in China and abroad.At the same time,a prospect of the comprehensive utilization of Macleaya spp.resourccs in thc further future is discussed.关键词
苄基异喹啉类生物碱/博落回/生物合成/微生物代谢工程Key words
Benzylisoquinoline alkaloid/Macleaya cordata (Willd.) R.Br./biosynthesis/microbial metabolic engineering引用本文复制引用
刘金凤,黄鹏,唐昭山,曾建国..博落回中苄基异喹啉类生物碱生物合成与代谢工程研究概况[J].中国现代中药,2017,19(10):1500-1504,5.基金项目
国家自然科学基金资助项目(31200615) （31200615）
湖南省科技重点计划(2016SK3002) （2016SK3002）
