川北医学院学报2017，Vol.32Issue(6)：821-823,3.DOI:10.3969/j.issn.1005-3697.2017.06.003
血浆脑钠肽检测在心力衰竭诊断中的应用评价
Clinical evaluation of BNP detection in diagnosis of heart failure
摘要
Abstract
Objective:To investigate the clinical value of brain natriuretic peptide (BNP) in the diagnosis of heart failure.Methods:A total of 71 cases of patients with heart failure were selected as observation group.In the same period,71 healthy subjects were selected as the control group.The levels of BNP,left ventricular ejection fraction (LVEF),BNP grade with different cardiac function and positive rate were compared between the two groups.Results:The LVEF in the observation group was significantly lower than that in the control group,and the levels of BNP was higher than that in the control group,the difference was statistically significant (P ＜0.05).The positive rate of grade Ⅰ was 53.33％,the positive rate of grade Ⅱ was 76.47％,the positive rate of grade Ⅲ was 95.00％,the positive rate of grade Ⅳ was 100.00％.The level of BNP in patients with grade Ⅳ cardiac function was significantly higher than that in grade Ⅰ,Ⅱ and Ⅲ patients,the difference was statistically significant (t =36.535,24.466,19.305,P ＜0.05).The level of BNP in patients with heart function grade Ⅲ was higher than that of patients with grade Ⅰ,and the difference was statistically significant (t =2.732,P ＜ 0.05).However,there was no significant difference between the level of BNP in the patients with cardiac function grade Ⅱ with these in the grade Ⅰ and Ⅲ.Conclusion:BNP detection has a good effect in the diagnosis of heart failure,which is helpful for early diagnosis,and the more serious the heart failure is,the higher the positive detection rate and detection value are.关键词
血浆脑钠肽/心力衰竭/检测率/诊断/应用价值Key words
Brain natriuretic peptide(BNP)/Heart failure/Detection rate/Diagnosis/Application value分类
医药卫生引用本文复制引用
王元芬..血浆脑钠肽检测在心力衰竭诊断中的应用评价[J].川北医学院学报,2017,32(6):821-823,3.基金项目
贵州省安顺市科技局课题[安市科合(2016)01号] （2016）
