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年轻血液延缓衰老研究进展

王秋 鲁思宇 李国林

国际老年医学杂志2017,Vol.38Issue(6):286-288,3.
国际老年医学杂志2017,Vol.38Issue(6):286-288,3.DOI:10.3969/j.issn.1674-7593.2017.06.012

年轻血液延缓衰老研究进展

Advance in Rejuvenescent Roles of Young Blood

王秋 1鲁思宇 1李国林1

作者信息

  • 1. 湖南师范大学生命科学学院蛋白质化学与发育生物学教育部重点实验室,长沙 410081 中国
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摘要

Abstract

Retarding aging process and age-related functional degeneration of organs is a difficult issue in aging research. Recent studies demonstrate that heterochronic parabiosis can effectively rejuvenate the aging phenotypes of several organs and even ex-tend the lifespan of the old animal. Heterochronic parabiosis is a technique that surgically splice a young animal and an old animal to-gether by connecting their skin from one side between front and back legs, and therefore they can share circulation systems. Further evidence illustrates that the injection of young plasma to old animal can also rejuvenate the aging phenotypes. All these results indicate that some specific factors that may mediate the effects of young blood on improving aging process. This paper reviews the advance in antiaging roles of young blood.

关键词

衰老/年轻血液/连体共生/GDF11/TIMP2

Key words

Aging/Young blood/Parabiosis/GDF11/TIMP2

引用本文复制引用

王秋,鲁思宇,李国林..年轻血液延缓衰老研究进展[J].国际老年医学杂志,2017,38(6):286-288,3.

基金项目

国家自然科学基金资助课题(31271257) (31271257)

国际老年医学杂志

OACSTPCD

1674-7593

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