国际老年医学杂志2017,Vol.38Issue(6):286-288,3.DOI:10.3969/j.issn.1674-7593.2017.06.012
年轻血液延缓衰老研究进展
Advance in Rejuvenescent Roles of Young Blood
摘要
Abstract
Retarding aging process and age-related functional degeneration of organs is a difficult issue in aging research. Recent studies demonstrate that heterochronic parabiosis can effectively rejuvenate the aging phenotypes of several organs and even ex-tend the lifespan of the old animal. Heterochronic parabiosis is a technique that surgically splice a young animal and an old animal to-gether by connecting their skin from one side between front and back legs, and therefore they can share circulation systems. Further evidence illustrates that the injection of young plasma to old animal can also rejuvenate the aging phenotypes. All these results indicate that some specific factors that may mediate the effects of young blood on improving aging process. This paper reviews the advance in antiaging roles of young blood.关键词
衰老/年轻血液/连体共生/GDF11/TIMP2Key words
Aging/Young blood/Parabiosis/GDF11/TIMP2引用本文复制引用
王秋,鲁思宇,李国林..年轻血液延缓衰老研究进展[J].国际老年医学杂志,2017,38(6):286-288,3.基金项目
国家自然科学基金资助课题(31271257) (31271257)