广西医学2018，Vol.40Issue(2)：143-144,2.DOI:10.11675/j.issn.0253-4304.2018.02.07
小剂量红霉素辅助治疗小儿毛细支气管炎的临床效果
Clinical efficacy of low-dose erythromycin for adjuvant treatment of children with bronchiolitis
马苗苗 1王斌锋 2杨永红 1刘晓会1
作者信息
- 1. 陕西省铜川市人民医院儿科,铜川市 727000
- 2. 陕西省铜川市人民医院普通外科,铜川市 727000
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy of low-dose erythromycin for the adjuvant treatment of bronchiolitis in children. Methods A total of 280 children with bronchiolitis were divided into observation group(n=140) and control group(n=140). Besides the conventional treatment performed in the two groups, the observation group was treated with erythromycin at a low dose of 10 mg/(kg·d) for five days,and the control group with an equivalent amount of 5％ glucose injection. The clinical efficacy,duration for pulmonary rales disappeared, hospital stay, improvement of milk-regurgitating symptoms, and incidence of adverse reactions were compared between the two groups. Results The observation group had higher total effective rate and higher improvement rate of milk-regurgitating symptoms as well as less duration for pulmonary rales disappeared and less hospital stay compared to the control group(all P<0. 05). There was no significant difference in the incidence rate of adverse effects between the two groups(P>0. 05). Conclusion The adjuvant therapy with low-dose erythromycin can effectively improve the symptoms of children with bronchiolitis,with a definite efficacy and good safety.关键词
毛细支气管炎/红霉素/临床效果/小儿Key words
Bronchiolitis/Erythromycin/Clinical efficacy/Children分类
医药卫生引用本文复制引用
马苗苗,王斌锋,杨永红,刘晓会..小剂量红霉素辅助治疗小儿毛细支气管炎的临床效果[J].广西医学,2018,40(2):143-144,2.
