解放军医药杂志2018，Vol.30Issue(1)：95-97,101,4.DOI:10.3969/j.issn.2095-140X.2018.01.025
右美托咪定辅助臂丛阻滞麻醉在加速康复外科中的应用效果
Effects of Dexmedetomidine Assisted Brachial Plexus Block Anesthesia on Enhanced Recovery after Surgery
摘要
Abstract
Objective To investigate effects of Dexmedetomidine assisted brachial plexus block anesthesia on enhanced recovery after surgery. Methods A total of 50 patients undergoing upper extremity surgery by intergroove bra-chial plexus block anesthesia during November 2015 and June 2016 were randomly divided into observation group and control group ( n=25 for each group) . At 10 min after successful anesthesia, observation group was injected with Dexme-detomidine by venous pump, while control group was assisted analgesia with appropriate doses of Midazolam combined with Fentanyl. Changes of mean arterial pressure ( MAP) , heart rate ( HR) , epinephrine ( E) and norepinephrine ( NE) concentrations were compared before anesthesia (T0), at 10 min after anesthesia (T1) and at 45 min after operation be-ginning (T2) in two groups. Condition of adverse reactions during the operation was recorded. Results In two groups, MAP, HR, E and NE levels at T1 were significantly higher than those at T1, while the levels at T2 were significantly low-er than those at T0 and T1; in observation group, the above levels at T2 were significantly lower than those in control group (P<0. 05). No adverse reaction was found in observation group. Conclusion Dexmedetomidine assisted brachi-al plexus block anesthesia may effectively inhibit stress reaction and accelerate recovery of patients.关键词
右美托咪定/臂丛阻滞/麻醉/加速康复外科Key words
Dexmedetomidine/Brachial plexus/Anesthesia/Enhanced rehabilitation surgery分类
医药卫生引用本文复制引用
杨艳超,蒋晨霞,崔淑珍,陈晶,怀乔,孟香果..右美托咪定辅助臂丛阻滞麻醉在加速康复外科中的应用效果[J].解放军医药杂志,2018,30(1):95-97,101,4.基金项目
石家庄市科技计划(151460643) （151460643）
