河北医学2018，Vol.24Issue(1)：30-34,5.DOI:10.3969/j.issn.1006-6233.2018.01.007
胃肠道间质瘤的CT表现及免疫组化分型关系的研究
The Relationship between CT Manifestations and Immunohistochemical Typing of Gastrointestinal Stromal Tumors
摘要
Abstract
Objective:To study the CT applied value in the diagnosis of gastrointestinal stromal tumor, and observe its performance and the relationship with immunohistochemical, so as to provide reference for stag-ing for clinical diagnosis and treatment plan. Methods:80 cases of gastrointestinal stromal tumors confirmed by operation and pathology in our hospital from April 2014 to April 2017 were selected as the research objects, including 48 cases of gastric lesions, 23 cases of small intestinal lesions, 7 cases of abdominal lesions, 1 case of esophageal lesions, 1 case of retroperitoneal lesions. All patients underwent CT scan. The location, size, shape, border, growth pattern, necrosis degree and calcification of the tumor were statistically analyzed, and compared with immunohistochemical typing. Results:In 80 patients, there were 24 cases, 19 cases, 9 cases and 28 cases of smooth muscle differentiation, nerve orientation differentiation, smooth muscle and nerve bidirectional differentiation and lack of differentiation. Eighty patients had 85 gastrointestinal stromal tumors, of which 40 were diameter less than 5cm, and 31 lesions were 5 ～ 10cm in diameter. The diameter of 14 lesions was more than 10cm. The contour of 52 lesions was fairly regular, and 33 lesions were irregular or lobule. The boundaries of 72 lesions were clear and 13 lesions were not clearly defined by the adhesion or infiltration of the surrounding area. 55 lesions were exogenous, 20 lesions were cross-wall growth, and 10 lesions were endoge-nous. There was no obvious necrosis in 40 lesions, 27 lesions were focal necrosis, and 18 lesions had extensive necrosis. Smooth muscle mass direction differentiation group > 10cm in diameter, mass increase, the mass proportion of extensive necrosis was obviously higher than that of neural differentiation of direction group, the smooth muscle and nerve two-way characteristics, lack of differentiation groups ( P<0.05) . Conclusion:CT examination is a clinical diagnosis of gastrointestinal stromal tumor is an effective way, to the CT manifestation of gastrointestinal stromal tumor give careful observation to determine tumor immune group tumble type, it is of great use value and significance, can further promote the use.关键词
胃肠道间质瘤/CT/免疫组化分型Key words
Gastrointestinal stroma/CT/Immunological histochemical typing引用本文复制引用
常莹,王冬梅,麦筱莉..胃肠道间质瘤的CT表现及免疫组化分型关系的研究[J].河北医学,2018,24(1):30-34,5.基金项目
江苏省自然科学基金项目,(编号:B200305) （编号:B200305）
