四川大学学报（医学版）2018，Vol.49Issue(1)：129-132,4.
生物型APC重建股骨近端瘤性骨缺损的保肢技术及疗效分析
Therapeutic Effect of Uncemented Allograft-prosthetic Composite for the Reconstruction of Tumorous Bone Defect
王延岭 1闵理 1段宏 1周勇 1张闻力 1石锐 1罗翼 1屠重棋1
作者信息
摘要
Abstract
Objective To investigate the surgical techniques and mid-term efficacy of reconstruction for proximal femur with allograft-prosthetic composite (APC).Methods Fifteen patients who underwent uncemented APC reconstruction of proximal femur after bone tumor resection were retrospectively evaluated.Image and physical examinations were taken on the 1st,3rd,6th,9th and 12th month after surgery and every 6 months thereafter to assess union condition,greater trochanteric bone absorption and myodynamia of abductors.Musculoskeletal Tumor Society (MSTS) and Harris Hip Score (HHS) were utilized to evaluate the function of hip joint.Results Seven male and eight female patients were included with average age of 25.1 years(17-56 years) and average followup of 32.8 months(18-48 months).Four patients had giant cell tumor of the bone,3 patients had osteosarcoma,3 patients had chondrosarcoma,2 patients had malignant fibrous histiotoma,2 patients had osteoblastoma and 1 patient had Ewing sarcoma.Unions occurred in the allograft-host bone interfaces of all patients in the period of 5-9 months postoperatively.Bone absorption in the allograft-host bone interfaces,dislocation,hypersensitivity of the allograft and acetabulum abrasion were not observed,while there were no metastasis and tumor recurrence.Three patients had periprosthetic fractures intraoperatively and were well fixed with cerclage.Absorptions in the greater trochanteric happened to 6 patients.All patients had mean MSTS and HHS scores of 11.3 (7-15) and 47.3 (40.3-58.5) preoperatively and 26.1 (24-29) and 80.1 (66.2-92.7) postoperatively.Conclusion Uncemented APC reconstruction is proper for young patients with long life expectancy and high demand of function that suffered from tumors of proximal femur.关键词
股骨近段/骨肿瘤/骨缺损/同种异体骨-假体复合物/保肢技术Key words
Proximal femur/Bone tumor/Bone defect/Allograft-prosthetic composite/Limb salvage technique引用本文复制引用
王延岭,闵理,段宏,周勇,张闻力,石锐,罗翼,屠重棋..生物型APC重建股骨近端瘤性骨缺损的保肢技术及疗效分析[J].四川大学学报（医学版）,2018,49(1):129-132,4.
