家畜生态学报2018，Vol.39Issue(1)：1-7,7.
睾酮对动物生殖和生长发育影响的研究进展
Research Progress on Effect of Testosterone on the Animal Reproduction and Growth
摘要
Abstract
Testosterone (T) is the primary male sex hormone,mainly produced by Leydig cells (LCs);it's of great significance to promote spermatogenesis and follicular development and to maintain physiological activities of other tissues and organs.The study found that T can regulate gene transcription and protein expression by binding to androgen receptor (AR),and can activate a series of signaling pathways to regulate the expression of related cytokines by binding to AR or other membrane receptors.Thus,T plays an important role in many aspects,such as the reproductive system,bone tissue,cardiovascular system,brain tissue and skin.At present,many researches on T focus on animal models,especially the molecular signaling pathways as hormones,but lacking the overall data from its source to function.Therefore,this review presented a general progress that the LCs differentiation and maturation,the T synthetic process and synthetic regulation,and T on animal reproduction and growth,which would provide some references for the further study of T.关键词
睾酮/睾丸间质细胞/生殖系统/调控机理/研究进展Key words
testosterone (T)/Leydig cells (LCs)/reproductive system/regulatory mechanism/research progress分类
农业科技引用本文复制引用
张阳海,李永,曹迪,鱼婷,高佳阳,潘传英..睾酮对动物生殖和生长发育影响的研究进展[J].家畜生态学报,2018,39(1):1-7,7.基金项目
陕西省重点研发计划(一般项目-农业领域)(No.2017NY-064) （一般项目-农业领域）
中国博士后科学基金第56批面上资助项目(No.2014M560809) （No.2014M560809）
西北农林科技大学大学生创新训练项目(No.1201610712021) （No.1201610712021）
