军事医学2017，Vol.41Issue(10)：822-824,3.DOI:10.7644/j.issn.1674-9960.2017.10.008
类孟买血型血清学特点及基因突变分析
Serological characteristics and gene mutation analysis of Para-Bombay blood group
摘要
Abstract
Objective To identify the Para-Bombay blood group on the basis of its serological characteristics .Methods ABO blood typing , H antigen detection , absorption and elution test , and saliva neutralization test were conducted for serological identification of ABO blood group .PCR-SSP was used to sequence FUT1 and FUT2 genes.Results Results of ABO genotyping of eight individuals of the Para-Bombay blood group were consistent with results of their serological blood typing.Among these cases, there were 3 cases of Amh,4 cases of Bmh,and 1 case of Abmh.The results of their FUT1 genotyping were h1h1 in 3 cases, h2h2 in 2 cases and h1h2 in 3 cases.Conclusion The differentce of agglutination intensity between Ac and Bc in reverse ABO blood typing and abnormal Oc agglutination is of greet significance for Para -Bombay blood group.关键词
类孟买血型/血清学鉴定/FUT1/FUT2/基因测序Key words
Para-Bombay blood group/serological identification/FUT1/FUT2/gene sequencing分类
医药卫生引用本文复制引用
周小芹,沈志辉,张乃淙,靳淞,梁声强..类孟买血型血清学特点及基因突变分析[J].军事医学,2017,41(10):822-824,3.基金项目
原南京军区医学科技创新资助项目(15MS105) （15MS105）
解放军175医院苗圃基金资助项目(16Y021) （16Y021）
