军事医学2017，Vol.41Issue(10)：825-829,5.DOI:10.7644/j.issn.1674-9960.2017.10.009
总前列腺特异性抗原在4～10ng/ml水平时前列腺穿刺活检的诊断效能及结果
Diagnostic efficiency and result of prostate biopsy for patients with t-PSA between 4.0 and 10 ng/ml
刘健男 1麦海星 1曲楠 1李学超 1王亚林 1黄晨 1陈立军1
作者信息
- 1. 军事医学科学院附属医院泌尿外科,北京 100071
- 折叠
摘要
Abstract
Objective To investigate the diagnostic efficiency and result of prostate biopsy for patients with t -PSA between 4.0 and 10 ng/ml.Methods This analysis was based on 20 qualified research papers from such lectronic databases as PubMed, MEDLINE, EMBASE and Cochrane from January 2010 until September 2017.Data extracted was analyzed using classic Meta-analysis with R software .The random or fixed effect model analysis was used to estimate the rate.Heterogeneity was analyzed using I 2 statistic.Results Totally 5481 patients were included in the 20 research papers. The positive rate of prostate biopsy was 20.6％, with t-PSA between 4.0 and 10 ng/ml, which was higher than the rate in the data from CUA Guide(2014).The difference was statistically significant .Conclusion Patients should be subjected to prostate biopsy if their t-PSA ranges 4.0 from 10 ng/ml regardless of the rate of f/t-PSA.The Gleason grade is relatively low when PSA is in the gray area , and the risk is also low.关键词
前列腺特异性抗原/前列腺穿刺/荟萃分析/Gleason评分Key words
prostate-specific antigen/prostate biopsy/Meta-analysis/Gleason grade分类
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刘健男,麦海星,曲楠,李学超,王亚林,黄晨,陈立军..总前列腺特异性抗原在4～10ng/ml水平时前列腺穿刺活检的诊断效能及结果[J].军事医学,2017,41(10):825-829,5.
