国际眼科杂志2018，Vol.18Issue(2)：248-251,4.DOI:10.3980/j.issn.1672-5123.2018.2.10
角膜塑形镜治疗亚洲儿童近视有效性和安全性的Meta分析
Efficacy and safety of orthokeratology to control myopia in Asia children: A Meta-analysis
摘要
Abstract
AIM: To assess the efficacy and safety of orthokeratology for reducing the progression of myopia in Asia children.?METHODS: Seven databases, including the Cochrane Library, Medline, EMbase, CBM, CNKI, VIP, and WanFang Data, were searched. The published languages were limited to English and Chinese. The risk bias tool provided by Cochrance cooperation and methodological index for non-randomized studies ( MINORS) scale were used to assess the risk bias of included studies (randomized controlled trials and controlled trials). The published biases of included studies were assessed with funnel plot. Meta-analysis was performed with Review Manager 5. 3.? RESULTS: Seven eligible studies, including 478 children, were included, 250 cases in ortho-k group, 228 cases in control group. The Meta-analysis indicated that change in axial length of ortho-k group was significantly less than the control group [WMD=-0. 31, 95％CI(-0. 35,-0. 26), P<0. 001]. Five studies observed adverse effects which all included the effect of positive staining of corneal fluorescein. One study reported chalazion in one child. None of the studies reported severe adverse events.? CONCLUSION: The overall findings suggested that orthokeratology might slow the progression of myopia in children of Asia.关键词
角膜塑形镜/亚洲/儿童/近视/眼轴长度/Meta分析Key words
orthokeratology/Asia/children/myopia/axial length/Meta-analysis引用本文复制引用
张祚洁,胡志强,舒敏,张伶俐,兰轲..角膜塑形镜治疗亚洲儿童近视有效性和安全性的Meta分析[J].国际眼科杂志,2018,18(2):248-251,4.基金项目
国家自然科学基金(No. 81373381) National Natural Science Foundation of China (No. 81373381) （No. 81373381）
