日用化学工业2018，Vol.48Issue(1)：31-36,6.DOI:10.13218/j.cnki.csdc.2018.01.007
羊栖菜多糖提取物及其润肤霜的保湿和抗氧化活性
Moisturizing and antioxidant activity of polysaccharide extract from Sargassum fusiforme and its application in moisturizing cream
摘要
Abstract
The sargassum polysaccharides (FSF)was extracted from Sargassum fusiforme by using ultrasonic cell disintegration-assisted water extraction and alcohol precipitation. Determination of antioxidant activity and moisturizing activity of the extract of FSF (EFSF)was carried out. This EFSF was used to prepare moisturizing cream,and its moisturizing activity was evaluated in vitro. The effect of the moisturizing cream on the antioxidant activity of the skin of the mouse was investigated by using the skin coating test. Results show that EFSF has strong free radical scavenging ability and better moisturizing activity than glycerol. The cream with EFSF also has high moisturizing activity:the water loss rate of 198 h in a dry environment is 4. 33％,the water loss rate of 198 h under the relative humidity of 43％ is 2. 36％. Skin coating experiments show that compared with the negative control group (cream contained only substrate)and with the positive control group (0. 3％arbutin moisturizing cream),this moisturizing cream with EFSF can significantly enhance the hydroxyl radical scavenging capacity (403. 65 U/mgprot),superoxide anion radical scavenging ability (810. 52 U/gprot),total antioxidant capacity (11. 58 U/mgprot),and T-SOD activity (81. 11 U/mgprot)in mouse skin,markedly increase hydroxyproline content (43. 49 mg/L)and reduce MDA content (2. 12 nmol/mgprot).关键词
润肤霜/羊栖菜/多糖提取物/保湿性能/抗氧化活性Key words
cream/Sargassum fusiforme/polysaccharide extract/moisturizing activity/antioxidant activity分类
化学化工引用本文复制引用
陈琳琳,谢志新,程晶,张文州,黄晓冬..羊栖菜多糖提取物及其润肤霜的保湿和抗氧化活性[J].日用化学工业,2018,48(1):31-36,6.基金项目
福建省中青年教师教育科研资助项目(JA15721 （）
JA15715) （）
泉州市指导性科技计划资助项目(2015ZD36 （）
2015ZD35) （）
福建省自然科学基金资助项目(2016J01175) （2016J01175）
