生殖医学杂志2018，Vol.27Issue(2)：117-122,6.DOI:10.3969/j.issn.1004-3845.2018.02.004
获卵数与IVF/ICSI累积活产率的相关性研究
Association of number of oocytes retrieved with cumulative live birth rate of IVF/ICSI
摘要
Abstract
Objective:To explore the correlation between the number of oocytes retrieved and cumulative live birth rate of IVF/ICSI.Methods:The data of 4 975 cycles undergone the first IVF cycle in our center from April 2014 to June 2015 were retrospectively analyzed.The patients were divided into six groups according to the number of oocytes retrieved:1-3 (Group A);4-6 (Group B);7-9 (Group C);10-15 (Group D);16-20 (Group E);＞20(Group F).The age,etiology of infertility,2PN rates,cumulative live birth rate and all embryos frozen rate for high risk of OHSS were compared among the six groups.The logistic multivariate analysis was done between age,number of oocytes retrieved & ovulation induced protocol and cumulative live birth rate.Results:With the increase of the number of oocytes retrieved,the cumulative live birth rate and all embryos frozen rate for high risk of OHSS were significantly enhanced (P＜0.05).The group F had the lowest rate of embryo transfer in the fresh cycle and the lowest 2PN rate (P＜0.05).The group A had the highest rate of no embryo transferable and the lowest live birth rate in the fresh cycle (P＜0.05).Logistic multivariate analysis showed that the live birth rate was significantly increased from group B to group F compared with group A,and the OR was 3.456 (2.562,4.662),5.845 (4.324,7.901),8.625 (6.446,11.539),13.001(9.401,17.961),17.389(12.168,24.845) respectively.The cumulative live birth rate in 35-39 years and ≥40 years old patients was significantly lower than that in the patients ≤30 years old,and the OR was 0.570(0.455,0.714),and 0.243(0.165,0.357)respectively.Conclusions:The cumulative live birth rate is significantly increased along with the number of oocytes retrieved.The number of oocytes retrieved is a strong independent predictor for cumulative live birth rate.关键词
获卵数/累积活产率/IVF/ICSI/年龄Key words
Number of oocytes retrieved/Cumulative live birth rate/IVF/ICSI/Age引用本文复制引用
潘荣,于玲,王涛,师娟子..获卵数与IVF/ICSI累积活产率的相关性研究[J].生殖医学杂志,2018,27(2):117-122,6.基金项目
社会发展科技攻关项目(2016SF-085) （2016SF-085）
