天然产物研究与开发2017，Vol.29Issue(12)：2134-2140,7.DOI:10.16333/j.1001-6880.2017.12.023
太子参茎叶多糖对免疫抑制小鼠免疫功能的影响
Effects of Radix pseudostellariae Stem and Leaf Polysaccharide on Immune Function of Immunosuppressed Mice
摘要
Abstract
This study was designed to elucidate the immuno-enhancement effects of Radix pseudostellariae stem and leaf polysaccharide (RPSLP) in immunosuppressed mice induced by cyclophosphamide (CY) treatment.100 mice were randomly divided,the immunosuppressed mice were given CY via intraperitoneal injection.Then the ratio of splenocytesproliferation in immunosuppressed mice was assayed and the immunological indexes in serum of mice were detected.The results showed that compared with CY model group,the spleen index in RPSLP group of mice was significantly decreased (P ＜ 0.01);the thymus index,phagocytic index,splenocyte proliferation,immunoglobulin (IgA,IgG,IgM),complement (C3,C4) and cytokines (IL-2,IL-4,IL-6,IFN-γ) content were significantly increased in different degree (P ＜ 0.05 or P ＜ 0.01).In conclusion,RPSLP enhanced the immune function of immunosuppressed mice induced by CY treatment.关键词
太子参茎叶/多糖/环磷酰胺/免疫抑制Key words
Radix pseudostellariae stem and leaf/polysaccharides/cyclophosphamide/immunosuppression分类
农业科技引用本文复制引用
檀新珠,陈语嫣,陈赛红,廖吕燕,黄一帆,马玉芳..太子参茎叶多糖对免疫抑制小鼠免疫功能的影响[J].天然产物研究与开发,2017,29(12):2134-2140,7.基金项目
福建省科技厅产学研专项(2014N5004) （2014N5004）
