武汉工程大学学报2018，Vol.40Issue(1)：8-16,27,10.DOI:10.3969/j.issn.1674-2869.2018.01.002
生物体内甲醛参与的化学反应研究进展
Advances in Chemical Reaction of Formaldehyde in Organisms
韩颜 1江海鹏 1巨修练1
作者信息
- 1. 武汉工程大学化工与制药学院,湖北 武汉 430205
- 折叠
摘要
Abstract
Aiming at the endogenous formaldehydes reacting with important molecules in organism,such as protein, nucleic acids and neurotransmitters, and affecting their structures and functions, we have systematically reviewed the research progress of endogenous formaldehyde production, the mechanism of toxicity and metabolic pathways in organisms. Recently,the most commonly used method for eliminating excess endogenous formaldehyde is to add the capture agents,however,whether the formaldehyde capture agent interferes the normal formaldehyde biochemical reaction is worth considering. Therefore,the paper proposes the metabolic regulation strategies to achieve formaldehyde balance of organisms,which is of great significance for comprehensively understanding and reducing the effects of endogenous formaldehyde on organisms.关键词
内源性甲醛/生物机体/毒性机制/代谢途径Key words
endogenous formaldehyde/organism/mechanisms of toxicity/metabolic pathway分类
生物科学引用本文复制引用
韩颜,江海鹏,巨修练..生物体内甲醛参与的化学反应研究进展[J].武汉工程大学学报,2018,40(1):8-16,27,10.
