中国全科医学2018，Vol.21Issue(2)：219-222,4.DOI:10.3969/j.issn.1007-9572.2018.02.21
2型糖尿病患者采用持续皮下胰岛素输注与胰岛素多次皮下注射治疗的成本效果比较研究
Comparing the Cost-effectiveness of Continuous Subcutaneous Insulin Infusion versus Multiple Daily Insulin Injections for the Treatment of Patients with Type 2 Diabetes Mellitus
杨昕娉 1周玲玲 2梁成 2李强3
作者信息
- 1. 300041天津市,天津医科大学三中心临床学院
- 2. 300171 天津市第三中心医院医保科
- 3. 300171 天津市第三中心医院院长办公室
- 折叠
摘要
Abstract
Objective To compare the cost-effectiveness of continuous subcutaneous insulin infusion(CSII) versus multiple daily insulin injections(MDII) for the treatment of patients with type 2 diabetes mellitus(T2DM).Methods A total of 271 T2DM patients admitted to the Department of Endocrinology, Tianjin Third Central Hospital from January 2016 to January 2017 were enrolled and assigned to Groups A(n=128) or B(n=143) according to different treatment. Patients in Group A received insulin via an insulin pump for 1 week, followed by subcutaneous insulin injections and/or oral antidiabetic therapy; subjects in Group B were given MDII or combination with oral antidiabetic therapy. The persistence of normal blood glucose levels after treatment, use of insulin and the cost of antidiabetics were recorded during the hospital stay.Results There were no significant differences in the persistence of normal blood glucose, the cost of antidiabetics or the total effective rate between Groups A and B(P>0.05). The use of insulin were significantly higher in Group A than in Group B, while cost-effectiveness was significantly lower in Group A than in Group B(P<0.05). In addition, the incremental cost-effectiveness ratio was 2.38 in Group B relative to Group A.Conclusion Based on our pharmacoeconomic analysis, CSII is superior to MDII in terms of its cost-effectiveness ratio and has a higher incremental cost-effectiveness ratio for the treatment of T2DM patients.关键词
糖尿病,2型/费用效益分析/胰岛素/输注泵Key words
Diabetes mellitus/type 2/Cost-benefit analysis/Insulin/Infusion pumps分类
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杨昕娉,周玲玲,梁成,李强..2型糖尿病患者采用持续皮下胰岛素输注与胰岛素多次皮下注射治疗的成本效果比较研究[J].中国全科医学,2018,21(2):219-222,4.
