中国人兽共患病学报2017，Vol.33Issue(12)：1066-1070,5.DOI:10.3969/j.issn.1002-2694.2017.12.003
新疆伊犁地区尼勒克县人群泡球蚴感染病例调查及nad2、cob基因片段分析
Emerging alveolar echinococcosis and gene fragments of Nad 2 and Cob in Nileke County, Yili area of Xinjiang, China
摘要
Abstract
We investigated the endemic situation of alveolar echinococcosis (AE) in Nileke County,Yili Prefecture,Xinjiang and its genetic diversity of Echinococcus multilocularis.Human AE cases in the county were retrospectively investigated including their location and surrounding ecological conditions.Sequence detection and analysis of nad2,cob gene fragments of AE mtDNA from patients was used to identify genotype variation.Results showed that a total of 48 AE cases were diagnosed and the first AE patient was identified in 1989 in the county.The 45.8％ of AE cases were found in the recent 5 years (2011-2015) and annual prevalence was 1.7 per 100 000.The patients were distributed along the Kashgar River,particularly intensive in Wulasitai Township.The 38.6％ of the patients were aged arranged 35-44 years old,64.6％ were male and 95.8％ were farmers and herdsmen.AE cases were confirmed further and there was only one haplotype by sequencing analysis from 11 AE clinical patients in the county.It suggests that Nileke County is AE foci,and alveolar echinococcosis with sequences conserved is an emerging disease in the county.关键词
泡球蚴病/多房棘球蚴病/基因变异/尼勒克县Key words
alveolar echinococcosis/Echinococcus multilocularis/gene variation/Nileke County分类
医药卫生引用本文复制引用
郭永忠,初伊明,阿尔新·卡德尔,郭宝平,周璨林,李军,张文宝,郭刚..新疆伊犁地区尼勒克县人群泡球蚴感染病例调查及nad2、cob基因片段分析[J].中国人兽共患病学报,2017,33(12):1066-1070,5.基金项目
国家自然科学基金项目(No.U1303203,No.31760734)Supported by the grants from the National Nature Science Foundation of China (No.U1303203,No.31760734) （No.U1303203,No.31760734）
