中国人兽共患病学报2017，Vol.33Issue(12)：1082-1088,7.DOI:10.3969/j.issn.1002-2694.2017.12.006
支原体感染与生殖系统肿瘤关联性研究的系统评价
Association of mycoplasma infection with genital system tumor: A system evaluation
摘要
Abstract
We explore the association of the mycoplasma infection with genital system tumor.Some index word including prostate cancer,cervical cancer,ovarian cancer and mycoplasma were used in some electronic databases (including PubMed,Web of Science,Chinese biomedical database,wanfang database,CNKI) to search literatures.The R software was used for the meta-analysis.The Newcastle-Ottawa Scale (NOS) was used to evaluate the quality of the literature.Publication bias was evaluated by funnel figure,and the fail-safe number (Nfs) was calculated to estimate the reliability of the meta-analysis.Result showed that 20 articles were included,the numbers of cases and controls were 2 345 and 2 728 respectively.The pooled OR of Ureaplasma urealyticum(Uu),Mycoplasma hominis(Mh),other mycoplasma,mixture of mycoplasma and the whole mycoplasma was 2.19(95％CI:1.27-3.79),1.74(95％CI:1.28-2.35),1.97(95％CI:1.03-3.77),3.54 (95％CI:1.33-9.41),1.29(95％CI:1.53-2.60),respectively.The fail-safe number of Uu,Mh,other mycoplasma and mixture of mycoplasma was 254,42,31,157 respectively.There are some possibility about the association between the mycoplasma infection and the genital system cancer;maybe the infection would increase the tumorigenesis risk.It is necessary to research further about these associations in different mycoplasmas respectively.关键词
支原体/生殖系统/肿瘤/Meta分析Key words
mycoplasma/genital system/cancer/meta analysis分类
医药卫生引用本文复制引用
洪翔,殷玥琪,连大帅,杨曼,王蓓..支原体感染与生殖系统肿瘤关联性研究的系统评价[J].中国人兽共患病学报,2017,33(12):1082-1088,7.基金项目
高等学校博士学科点专项科研基金(No.20130092110048)Funded by the Doctoral Program Foundation of Institutions of Higher Education of China (No.20130092110048) （No.20130092110048）
