长春中医药大学学报2018，Vol.34Issue(1)：40-42,3.DOI:10.13463/j.cnki.cczyy.2018.01.013
益肾安神口服液特征图谱研究
Study on the characteristic spectrum of Yishen Anshen oral liquid
摘要
Abstract
Objective To establish a method of characteristic atlas for Yishen Anshen oral liquid,and to evaluate the quality of oral liquid entirely. Methods Kromasil 100-5 C18 chromatographic column was used (4.6 mm×250 mm, 5 μm); acetonitrile was used as mobile phase A, and water was used as mobile phase B, gradient elution. The flow rate was 1.0 mL/min and the detected wavelength was 210 nm. The traditional Chinese medicine fingerprint calculation software was used to calculate, establish the characteristic atlas, and classify the characteristic peaks, and on this basis,investigate the similarity between the batches of Yishen Anshen oral liquid.Results There were 10 common peaks in the characteristic spectrum of Yishen Anshen oral liquid.The relative retention time of the common peaks in the precision, repeatability and stability tests were all less than 0.5% RSD. The similarity of the 10 batches of samples was good, and the similarity was over 0.85. On the basis of the established characteristic map, the peaks of 10 characteristic peaks are assigned. Conclusion The method is simple, accurate and easy to operate, and provides the basis and method for further controlling the quality of Yishen Anshen oral liquid.关键词
益肾安神口服液/特征图谱/五味子醇甲Key words
Yishen Anshen oral liquid/characteristic spectrum/schisandrin分类
医药卫生引用本文复制引用
赵源慧,杨喆茗,白冰,徐建,李长惠,王宝成..益肾安神口服液特征图谱研究[J].长春中医药大学学报,2018,34(1):40-42,3.基金项目
吉林省重大科技招标专项(20150203008YY). （20150203008YY）
