广西医科大学学报2018，Vol.35Issue(1)：41-45,5.DOI:10.16190/j.cnki.45-1211/r.2018.01.011
曼月乐与孕三烯酮治疗子宫腺肌病疗效比较的Meta分析
Comparision of the efficacy of mirena and gestrinone in the treatment of adenomyosis:a meta-analysis
闫姗姗 1蒋凤艳1
作者信息
- 1. 广西医科大学第一附属医院妇科,南宁530021
- 折叠
摘要
Abstract
Objective:To evaluate the efficacy and safety of mirena and gestrinone in the treatment of adenomyosis by means of evidence-based medicine.Methods:China National Knowledge Infrastructure (CNKI),Wanfang Med Database,Pubmed,Cochrane Library,etc.were retrieved for controlled clinical trials (CCTs) and randomized controlled trials (RCTs) of mirena and gestrinone for adenomyosis.The extracted data was analyzed with the RevMan 5.3 software.Results:6 RCTs and 3 CCTs involving 706 patients met the inclusion criteria.The meta-analysis showed that in patients treated with mirena,the dysmenorrhea score (Visual Analogue Scale/ Score,VAS),menstrual blood volume,endometrial thickness,uterine volume and the incidence of adverse reactions were significantly decreased,compared to those treated with gestrinone (P＜0.05).Conclusion:The current evidence showed that mirena was safer and more effective than gestrinone in the treatment of adenomyosis.Mirena could be used as first choice for patients with no contraindications and no planning of pregnancy.关键词
曼月乐/孕三烯酮/子宫腺肌病/临床对照试验/疗效Key words
mirena/gestrinone/adenomyosis/controlled clinical trials/efficacy分类
医药卫生引用本文复制引用
闫姗姗,蒋凤艳..曼月乐与孕三烯酮治疗子宫腺肌病疗效比较的Meta分析[J].广西医科大学学报,2018,35(1):41-45,5.
