广西医科大学学报2018，Vol.35Issue(1)：45-48,4.DOI:10.16190/j.cnki.45-1211/r.2018.01.012
托特罗定联合缩泉丸加减治疗绝经后妇女膀胱过度活动症的临床疗效观察
Effect of tolterodine combined with Suoquan pill on overactive bladder in postmenopausal women
摘要
Abstract
Objective:To investigate the clinical effect of tolterodine combined with Suoquan pill on overactive bladder (OAB) in postmenopausal women.Methods:From January 2015 to December 2016,40 OAB postmenopausal women treated in our hospital were selected and randomly divided into an observation group and a control group,with 20 cases in each group.The patients in the control group received tolterodine treatment,and those in the observation group were treated as the control group with addition of Suoquan pill.The clinical effect,the quality of life,OAB symptom scores,urinary flow rate,and the levels of estradiol and follicle-stimulating hormone (FSH) in serum were compared.Results:The total response rate in the observation group was significantly higher than that in the control group (P＜ 0.05).After treatment,urinary output,mean urinary flow rate,maximum flow rate and serum FSH level were significantly increased in the observation group,compared with the control group (P＜0.05).The QOL and OABSS scores in the observation group were markedly lower than those in the control group (P＜ 0.05),but no significant difference was found in the level of estradiol between the two groups (P＜ 0.05).Patients treated with Suoquan pill had lower risk of adverse reactions.Conclusion:Tolterodine combined with Suoquan pill for the treatment of OAB in postmenopausal women was effective.It could improve patients' clinical symptoms and reduce the incidence of adverse reactions.关键词
缩泉丸/绝经后妇女/膀胱过度活动症Key words
Suoquan pill/postmenopausal women/overactive bladder分类
医药卫生引用本文复制引用
鹿英强,李大勇,王丽霞,袁明殿..托特罗定联合缩泉丸加减治疗绝经后妇女膀胱过度活动症的临床疗效观察[J].广西医科大学学报,2018,35(1):45-48,4.基金项目
国家自然科学基金资助项目(No.81173273) （No.81173273）
