摘要
Abstract
Objective:To study the value of pulse-indicated continuous cardiac output (PiCCO) in the evaluation of severe heart disease.Methods:90 patients with severe heart disease treated in our hospital from October 2015 to February 2017 were selected and randomly divided into a control group and an observation group,with 45 cases in each group.The patients in the control group were treated with routine therapy after operation.The patients in the observation group were treated as the control group with addition of PiCCO monitoring.The cardiac function index (CFI),extravascular pulmonary edema index (EVLWI),peripheral vascular resistance index (SVRI) and central venous pressure (CVP) after 4 h,12 h,24 h,and 48 h of operation were detected.Serum brain natriuretic peptide (BNP) level was measured,and the correlation between BNP level and cardiac function was analyzed.Results:The use of vasoacrive drugs,ICU hospital days,mechanical ventilation time and the incidence ofventricular arrhythmia were significantly lower than those in the control group (P＜0.05).At 24 h and 48 h after operation,the CFI and SVRI in the observation group were significantly higher than those at 4 h and 12 h post-operation,while EVLWI,CVP and serum BNP level were significantly lower (P＜0.01).At 12 h after operation,the CFI in the observation group was notably increased,whereas the EVLWI and serum BNP level were decreased,compared with those at 4 h post-operation (P＜0.01).Pearson correlation analysis showed that the serum BNP level was negatively correlated with CFI (r=-4.891,P=0.000),and positively correlated with EVLWI (r=5.628,P=0.000).Conclusion:PiCCO could effectively reflect the hemodynamic change of patients with severe heart disease,and predict patients' cardiac function and complications,which might help to improve the therapeutic effect.关键词
脉搏指示连续心排血量/重症心脏病/血流动力学Key words
PiCCO/severe heart disease/hemodynamics分类
医药卫生
