中国临床保健杂志2017，Vol.20Issue(6)：665-670,6.DOI:10.3969/J.issn.1672-6790.2017.06.012
益气养阴活血法对2型糖尿病前期疗效和安全性的系统评价
Effectiveness and safety of Tonifying Qi,nourishing Yin and activating blood method on pre-diabetes:a sys-tematic review
摘要
Abstract
Objective To assess the effectiveness and safety of Tonifying Qi,nourishing Yin and activating blood method on pre-diabetes.Methods The relevant data from the founding time to December 2013 in CBMDisc, CMAC,CNKI,VIP,WanFang Data,PubMed,EMbase,Web of Science were retrieved by computer and was adopted in this randomized controlled trials about the Tonifying Qi,nourishing Yin and activating blood method combination life intervene in the treatment of pre-diabetes.After two reviewers had independently screened the documents,extracted data and evaluated the quality of included trials,the Cochrane Collaboration′s software RevMan 5.1 was used for me-ta-analysis.Results A total of 17 studies involving 1497 patients were included.The results of meta analysis sugges-ted that,compared with the control group,combination with the Tonifying Qi,nourishing Yin and activating blood method could reduce the incidence of diabetes,increase the incidence of impaired glucose return to normal.There were statistical differences in fasting blood-glucose and 2-hour post-meal blood glucose between two groups,and was not sta-tistical differences on effects of glycosylated hemoglobin.The results suggest that the effectiveness of Tonifying Qi, nourishing Yin and activating blood method on pre-diabetes may be superior to the control group due to low qualit of inclusion trials.There were three studies reported adverse events and no serious adverse event was reported.Conclu-sion Based on current clinical evidence,the clinical effects of Tonifying Qi,nourishing Yin and activating blood method is better than the control group.However,more double-blind multi-center RCTs with high quality,large sample are required for further verification.关键词
糖尿病,2型/益气养阴/益气活血/生活方式/评价研究Key words
Diabetes mellitus/type 2/Reinforcing qi nourishing yin/Reinforcing qi activat blood/Life style/Evaluation studies分类
医药卫生引用本文复制引用
徐桂琴,杨骏,万阳,李雪苓..益气养阴活血法对2型糖尿病前期疗效和安全性的系统评价[J].中国临床保健杂志,2017,20(6):665-670,6.基金项目
2012年度国家中医临床研究基地业务建设科研专项课题(JDZX2012002) （JDZX2012002）
