中国临床保健杂志2018，Vol.21Issue(1)：10-14,5.DOI:10.3969/J.issn.1672-6790.2018.01.004
消瘀接骨散外敷配合电磁波谱治疗仪照射辅助治疗类风湿关节炎的效果及其对炎性指标的影响
Effect of XiaoYuJieGu powder combined with irradiation therapy on rheumatoid arthritis and its inflammation marker
摘要
Abstract
Objective To explore the effect of XiaoYuJieGu powder combined with irradiation therapy(TDP)on rheumatoid arthritis(RA)and its effect on tumor necrosis factor(TNF-α),interleukin 10(IL-10),interleukin 17 (IL-17).Methods A total of 60 patients with RA were selected and randomly divided into study group and control group,30 cases in each group.The control group was given conventional treatment,and the study group was treated with XiaoYuJieGu powder and TDP radiation based on the conventional treatment.Result After treatment,DAS28-3 score of RA patients were decreased in both groups,the DAS28-3 score of study group was lower than control group(P<0.01). The main symptoms scores of the two groups(joint pain,joint tenderness joint swelling and stiffness)were significantly de-creased(P<0.01);the improvement of joint tenderness,joint swelling and stiffness symptoms in the study group were better than the control group(P<0.05).CRP,RF,ESR,GPI,anti CCP immunoglobulin were reduced and complement C3,C4 were increased(P<0.05)in the study group.In the control group,there was no significant change in GPI,the complement C3 was increased,and the rest of the indexes were decreased(P<0.05).The study group was better than the control group(P<0.05)in decreasing ESR,CRP,anti CCP and increasing C3;TNF-αand IL-17 decreased and IL-10 in-creased in the two groups(P<0.05).After treatment,the study group was superior to the control group in reducing IL-17 and increasing IL-10(P<0.05).Conclusions XiaoYuJieGu powder combined with TDP can decrease the inflammatory indexes,while increase anti inflammatory cytokines in patients with RA and improve the clinical remission rate.关键词
关节炎,类风湿/中药外敷/电磁波谱治疗仪/肿瘤坏死因子类/白细胞介素类Key words
Rheumatoid arthritis/Exiernal applications(TCD)/TDP/Tumor necrosis factors/Interleukins分类
医药卫生引用本文复制引用
葛瑶,刘健,黄传兵,张皖东,汪元,范海霞,曹云祥..消瘀接骨散外敷配合电磁波谱治疗仪照射辅助治疗类风湿关节炎的效果及其对炎性指标的影响[J].中国临床保健杂志,2018,21(1):10-14,5.基金项目
国家临床重点专科建设项目资助[财社(2013)239号]国家临床重点专科中医适宜技术临床应用开放基金项目(2015AKJJ006) （2013）
