中国临床保健杂志2018，Vol.21Issue(1)：100-103,4.DOI:10.3969/J.issn.1672-6790.2018.01.028
急诊监护病房老年患者呼吸机相关性肺炎的病原菌分布及耐药性分析
Distribution and antimicrobial resistance of pathogens isolated from elderly patients with ventilator-associated pneumonia in EICU
王海云 1朱健 1周龙女 1王俏 1朱虹2
作者信息
- 1. 上海交通大学医学院附属第九人民医院,急诊科,上海200011
- 2. 上海交通大学医学院附属第九人民医院,临床医学院临床教研室,上海200011
- 折叠
摘要
Abstract
Objective To explore the distribution and antimicrobial resistance of pathogens in elderly patients with ventilator-associated pneumonia(VAP)in emergency intensive care unit(EICU),provide a reference for clinical reasonable use of antibiotics.Methods Two hundred and thirty elderly patients with VAP in EICU of our hospital from June 2012 to June 2017 were analyzed retrospectively.The pathogens and their antimicrobial susceptibility were detected and analyzed.Results Three hundreds and twelve strains of pathogenic bacteria were isolated from 230 patients,inclu-ding 227 strains of gram-negative bacteria,accounting for 72.8%;57 strains of gram-positive bacteria accounting for 18. 3%;28 strains of fungi,accounting for 9.0%.Drug Susceptibility test showed that the antimicrobial resistance of Acine-tobacter baumannii was the most severe,and only sensitive to amikacin,cefoperazone/sulbactam.Klebsiella pneumoniae, Escherichia coil and Enterobacter cloacae were susceptible to imipenem,metropenem,amikacin,cefoperazone/sulbactam and pipercillin/tazobactam.Pseudomonas aeruginosa was sensitive to amikacin,pipercillin/tazobactam,levofloxacin and ciprofloxacin.Staphylococcus aureus,Enterococcus and Staphylococcus epidermidis were susceptible to linezolid vanco -mycin and tigecycline.Most pathogens were resistant to multiple antibiotics.Conclusions Gram-positive bacteria are the main pathogens in elderly patients with VAP of EICU.Most pathogens are resistant to multiple antibiotics,which sug-gests that antibiotic therapy should be based on etiology and antimicrobial resistance surveillance results.关键词
肺炎,呼吸机相关性/重症监护病房/抗药性/老年人Key words
Pneumonia/ventilator-associated/Intensive care units/Drug resistance/Aged分类
医药卫生引用本文复制引用
王海云,朱健,周龙女,王俏,朱虹..急诊监护病房老年患者呼吸机相关性肺炎的病原菌分布及耐药性分析[J].中国临床保健杂志,2018,21(1):100-103,4.
