肿瘤预防与治疗2017，Vol.30Issue(5)：359-363,5.DOI:10.3969/j.issn.1674-0904.2017.05.007
108例脑胶质瘤患者的预后影响因素分析
Prognostic Factors Analysis of 108 Patients with Brain Glioma
吕凤琼 1黄伟 2林爱国 3周忠惠 1梅丽华 1魏厚禄3
作者信息
- 1. 629000四川遂宁,遂宁市中心医院全科医学科
- 2. 629000四川遂宁,遂宁市中心医院脑外科
- 3. 629000四川遂宁,遂宁市第一人民医院脑外科
- 折叠
摘要
Abstract
Objective:To explore the related factors of survival and prognosis of brain glioma.Methods:108 patients who have been confirmed with brain glioma during surgery from 2006 to 2014 were included for analysis retrospectively.The factors including sex,age,and Karnosky Performance Scale (KPS) score before surgery,surgical excision of part or all of the tumor,radiation treatment and so on were recorded.The COX regression was performed for the prognostic analysis.Results:The 1-,2-and 3-year survival rate was 92％,84％ and 67％,respectively;the median survival time was 49 months.The COX regression analysis showed age,pathological grading,KPS score,radiotherapy and the level of Ki67/EGFR were independently related to prognosis.In high pathological grading population,the result showed the KPS score and chemotherapy were the independently prognostic factors.Conclusion:Better prognostic glioma patients was depending on median age,low pathological grading,high KPS score,radiotherapy and low expression of Ki-67/EGFR.In the patients with high pathological grading,high KPS scores and chemotherapy were positively related to better survival outcome.关键词
脑胶质瘤/预后因素/生存分析Key words
Brain glioma/Prognostic factors/Survival analysis分类
医药卫生引用本文复制引用
吕凤琼,黄伟,林爱国,周忠惠,梅丽华,魏厚禄..108例脑胶质瘤患者的预后影响因素分析[J].肿瘤预防与治疗,2017,30(5):359-363,5.
