鲍治诚 1张露远 1吴亚平 1陆丽云 1唐晴 1钱小燕1
作者信息
- 1. 215300 江苏省昆山市第一人民医院神经内科
- 折叠
摘要
Abstract
Objective To investigate the effects of Xingnaojing injection on cerebral edema and serum NSE Levels after cerebral hemorrhage in the elderly.Methods Ninety-four patients of acute cerebral hemorrhage who received therapy from June 2014 to March 2016 in First People's Hospital of Kunshan City,Jiangsu Province were selected as research objects.According to the treatment of single and double number,they were divided into observation group and control group.According to the patient's physical condition,they were given to the injection of glycerol fructose,furosemide or mannitol and other dehydration under the effect of intracranial pressure injection.Observation group of patients on this basis plus Xingnaojing injection.The cerebral edema,neurological function recovery and serum NSE levels were compared between the two groups after hemorrhage.Results The total effective rate was 91.49％,which was higher in the observation groupthan in the control group 76.59％ (x2 =3.887,P =0.048).After treatment,the NIHSS score of the observation group was lower than that of the control group [(3.46 ± 0.61) vs.(5.73 ± 0.82),t =15.227,P ＜ 0.05].The edema volume and edema volume of the observation group and the control group were compared[(2.19 ± 0.54) ml vs.(4.16 ± 0.85) ml,t =13.471,P =0.000,(2.37 ± 0.74) ml vs.(4.06 ± 1.03) ml,t =9.165,P =0.000],the difference was statistically significant;On the 7th day after treatment,the NSE,CRP of the observation group compared with the control group,[(6.47 ± 3.23)μg/L vs.(13.01 ± 2.76) μg/L,t =10.533,P ＜ 0.05,(5.76 ± 2.41) pg/L vs.(12.70 ± 2.84) μg/L,t =12.773,P =0.000].Conclusion Xingnaojing injection on the treatment of cerebral hemorrhage effect is obvious,not only can effectively smaller brain edema,rapid recovery of the patient's brain function,reduce serum NSE secretion,improve patient prognosis.Worthy of extensive clinical use in the future.关键词
脑出血,急性/醒脑静注射液/神经元特异烯醇化酶Key words
Cerebral hemorrhage/Xingnaojing injection/Neuron-specific enolase
