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细菌对氟苯尼考的耐药机制研究进展

刘蔚雯 汪洋

中国动物传染病学报2018,Vol.26Issue(1):1-6,6.
中国动物传染病学报2018,Vol.26Issue(1):1-6,6.

细菌对氟苯尼考的耐药机制研究进展

MECHANISMS OF BACTERIAL RESISTANCE TO FLORFENICOL

刘蔚雯 1汪洋1

作者信息

  • 1. 中国农业大学动物医学院,北京 100193
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摘要

Abstract

As a new broad spectrum amphenicol, florfenicol performs excellent anti-bacterial infections and is now widely used in animal clinical treatment. However, the extensive usage of florfenicol leads to the increasing trends of bacterial resistance. Particularly, a few florfenicol resistance genes also causes no efficacy of oxazolidinones, which are effective in human clinical treatment for multi-resistant bacterial infections including methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci,therefore posing a significant threat to public health. This review summarizes the current knowledge of mechanisms of bacterial resistance to florfenicol in order to provide the theoretical guidance for control of the occurrence and dissemination of florfenicol-resistant strains and the reference data for rational administration of drugs in veterinary practice as well as the risk assessment for human and animal health.

关键词

氟苯尼考/耐药性/耐药机制

Key words

Florfenicol/resistance/mechanisms

分类

农业科技

引用本文复制引用

刘蔚雯,汪洋..细菌对氟苯尼考的耐药机制研究进展[J].中国动物传染病学报,2018,26(1):1-6,6.

中国动物传染病学报

OA北大核心CSTPCD

1674-6422

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