中华耳科学杂志2017，Vol.15Issue(6)：705-708,4.DOI:10.3969/j.issn.1672-2922.2017.06.019
中耳胆固醇肉芽肿与血脂代谢异常的相关性研究
Correlations Between Middle Ear Cholesterol Granuloma and Dyslipidemia
摘要
Abstract
Objective To study the relationship between middle ear cholesterol granuloma and dyslipidemia by analyzing characteristics of lipid metabolism in patients with middle ear cholesterol granuloma.Methods Serum triglyc-eride (TG),total cholesterol (TC),low density lipoprotein cholesterol (LDL),high density lipoprotein cholesterol (HDL),apolipoprotein A1(APOA1)and apolipoprotein B(APOB)contents in 57 cases of middle ear cholesterol granu-loma were retrospectively analyze and compared to 57 age and gender matched cases of chronic otitis media without cholesterol granuloma (based on pathological and imaging diagnoses).Results TC,LDL,APOA1,LDL/APOA1,and APOB/APOA1 levels in cases of middle ear cholesterol granuloma were higher than in cases without cholesterol granu-loma(P<0.05),but TG,HDL,APOB and HDL/APOB levels showed no difference between the two groups(P>0.05).Logistic multiple factors analysis showed that TC,LDL were risk factors for middle ear cholesterol granuloma.Conclu-sion Patients with middle ear cholesterol granuloma show higher lipid levels than patients without middle ear cholester-ol granuloma,and TC,LDL,APOA1,LDL/APOA1 and APOB/APOA1 levels show correlation with the onset of mid-dle ear cholesterol granuloma.关键词
胆固醇肉芽肿/慢性中耳炎/血脂代谢Key words
Cholesterol Granuloma/Chronic Otitis Media/Blood Lipid Metabolism分类
医药卫生引用本文复制引用
张坤,张恩东,曲芃,付涛,王志远,陈晓庆..中耳胆固醇肉芽肿与血脂代谢异常的相关性研究[J].中华耳科学杂志,2017,15(6):705-708,4.基金项目
新型骨导助听器骨振动器的研发及实用,编号:2015-6-009-YY （）
