中国现代中药2017，Vol.19Issue(9)：1233-1239,7.DOI:10.13313/j.issn.1673-4890.2017.9.005
臭参正丁醇萃取部位化学成分研究
Chemical Constituents from n-BuOH Extract of Codonopsis pilosula
摘要
Abstract
Objective:To study the chemical constituents from the n-butanol extract of Codonopsis pilosula produced in Yunnan province.Methods:The chemical constituents were isolated by various column chromatography.Their structures were identified by NMR and MS.Results:Twenty-one known compounds were isolated from n-butanol extract of C.pilosula from in Yunnan province.Their structures were identified as 7R,8R-threo-4,7,9,9'-tetrahydroxy-3-methoxy-8-O-4'-neolignan-3'-O-β-D-glucopyranoside (1),catechin-7-O-β-D-glucopyranside (2),syringin (3),coniferin (4),tangshenoside Ⅱ(5),(Z)-4-hydroxycinnamyl alcohol 4-O-.β-D-glucopyranoside (6),2-hydroxymethylphenyl-1-O-β-D-glucopyranoside (7),benzyl-6-O-β-D-xylopyranosyl-O-β-D-glucopyranoside (8),(2E)-2-(3-D-glucopyranosyloxy)-3-phenyl-2-propenoic acid (9),(2Z)-2-(β-D-glucopyranosyloxy)-3-phenyl-2-propenoic acid (10),2-phenylethyl 6-O-β-D-xylopyranosyl-O-β-D-glucopyranoside (11),tangsheno side Ⅰ (12),3-hydroxy-2-｛4-[(1E)-3-hydroxyprop-l-en-l-yl]-2-methoxyphenoxy｝ propylβ-D-glucopyranoside (13),(2E)-4-hydroxy-2-hexenoic acid (14),(2E)-3-methyl-2-pentenedioic acid (15),5-acetylshikimic acid (16),tryptophan (17),adenosine (18),niacin (19),caffeine (20),and 5-(methoxycarbonyl)-2-pyrrolidone (21),respectively,by spectroscopic methods.Conclusion:Among these substances,compounds 8,9,11,13 and 21 were isolated from C.pilosula for the first time.关键词
臭参/苯丙素苷/生物碱Key words
Codonopsis pilosula/phenylpropanoids/alkaloids引用本文复制引用
庄小翠,晏永明,张庆芝,程永现..臭参正丁醇萃取部位化学成分研究[J].中国现代中药,2017,19(9):1233-1239,7.基金项目
云南省生物科技重大项目(2014FC002) （2014FC002）
