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响应面法优化何首乌二苯乙烯苷类化合物提取工艺

唐静 黄磊

中国现代中药2017,Vol.19Issue(9):1291-1295,5.
中国现代中药2017,Vol.19Issue(9):1291-1295,5.DOI:10.13313/j.issn.1673-4890.2017.9.016

响应面法优化何首乌二苯乙烯苷类化合物提取工艺

Response Surface Analysis of Extraction for TSG from Polygonum multiflorum

唐静 1黄磊2

作者信息

  • 1. 华中科技大学同济医学院附属梨园医院药剂科,湖北 武汉430077
  • 2. 武汉市武昌医院,湖北 武汉430063
  • 折叠

摘要

Abstract

Objective:To optimize the extraction for 2,3,5,4-tetrahydroxyl diphenylethylene-2-O-glucoside (TSG)from Polygonum multiflorum with response surface methodology.Methods:Extraction temperature,liquid-solid ratio,ethanol volume,which designed by central composite were evaluated by TSG extraction yield.The response surface methodology was used to establish the prediction model of regression equation,and confirm the optimal extraction in TSG.Results:The optimal protocol for TSG extraction was at 54 ℃ in 72% ethanol with a liquid-solid ratio of 18 ∶ 1,the extraction yield reached 2.75%.Conclusion:The selected parameters provide a theoretical basis for TSG extraction.

关键词

响应面/何首乌/二苯乙烯苷/提取

Key words

Response surface analysis/Polygonum multiflorum/TSG/extraction

引用本文复制引用

唐静,黄磊..响应面法优化何首乌二苯乙烯苷类化合物提取工艺[J].中国现代中药,2017,19(9):1291-1295,5.

基金项目

华中科技大学自主创新基金(2014QN072) (2014QN072)

中国现代中药

OACSTPCD

1673-4890

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