磁共振成像2018，Vol.9Issue(2)：92-96,5.DOI:10.12015/issn.1674-8034.2018.02.003
超急性期轻度脑外伤患者静息态功能性磁共振成像研究
Study on resting-state functional magnetic resonance imagingin hyperacute phase of mild traumatic brain injury
摘要
Abstract
Objective: To investigate the abnormal changes of brain function in the hyperacute period (<24 h) patients with mild traumatic brain injury (mTBI) by using the amplitude of low-frequency fluctuation (ALFF) in resting state functional magnetic resonance imaging (rs-fMRI). Materials and Methods: 52 mTBI patients (mTBI group) and matched 21 healthy subjects (control group) underwent rs-fMRI examination. The DPARSF software was used to preprocess the fMRI data, the ALFF was compared between the mTBI and control group. Results: Compared with the healthy control group, the mTBI group showed significantly decreasing ALFF values in cerebellum posterior lobe, right middle occipital gyrus and postcentral gyrus. And the ALFF values increased in bilateral frontal lobe, bilateral caudate,medial frontal gyri and insula. Conclusions: In the case of normal routine MRI findings, ALFF technology showed to be more sentitive in detecting rs-fMRI abnormalities in patients with hyperacute mTBI.关键词
超急性期/颅脑损伤/磁共振成像,功能性/低频振幅Key words
Hyperacute period/Craniocerebral trauma/Magnetic resonance imaging/functional/Amplitude of low-frequency fluctuation分类
医药卫生引用本文复制引用
鲁兴启,李洁,张树飞,丁建平..超急性期轻度脑外伤患者静息态功能性磁共振成像研究[J].磁共振成像,2018,9(2):92-96,5.基金项目
杭州市重点专病专科项目(编号:20150733Q19) This work was part of Hangzhou Key Specialty Disease Specialist Project(No.20150733Q19). （编号:20150733Q19）
