磁共振成像2018，Vol.9Issue(2)：113-116,4.DOI:10.12015/issn.1674-8034.2018.02.007
磁共振扩散峰度成像对腰椎间盘退变的诊断价值
Assessment of diffusion kurtosis imaging in lumbar intervertebral disc degeneration
摘要
Abstract
Objective: To investigate the value of diffusion kurtosis imaging (DKI) related parameters in assessing lumbar intervertebral disc degeneration. Materials and Methods: T2WI and DKI were performed on 81 subjects. DKI related parameters: mean kurtosis (MK) and mean diffusivity (MD) of nucleus pulposus (NP) were measured and correlated with Pfirrmann grades,disc level,and gender.ANOVA and post hoc tests were employed to compare MK and MD values of different Pfirrmann grades, as well as the values in different disc levels. Associations between MK, MD values and Pfirrmann grades were tested using Spearman rank correlation.Two-sample t-test was applied for the gender differences. Results: Pfirrmann grades were positively correlated with MK values (r=0.922, P<0.01) and negatively correlated with MD values (r=-0.921, P<0.01)in the NP.MK value in L5/S1 level(0.89±0.32)was higher than that in L1/L2 (0.82±0.14) and L2/L3 (0.84±0.23) (P<0.05) level, MD value in L5/S1 level (1.83±0.30) was lower than that in L1/L2 (1.89±0.14) and L2/L3 (1.86±0.19) (P<0.05) level. There was no statistical significances in MK and MD values of each level between males and females (P>0.05). Conclusions: DKI is feasible to assess early lumbar intervertebral disc degeneration. MK and MD values are correlated with Pfirrmann grades and spinal level, and have no correlation with gender.关键词
椎间盘退化/腰椎/扩散峰度成像/磁共振成像Key words
Intervertebral disc degeneration/Lumbar vertebrae/Diffusion kurtosis imaging/Magnetic resonance imaging分类
医药卫生引用本文复制引用
曾菲菲,查云飞,胡磊,林苑,龚威,陈翩翩,柳柏玉,陆雪松..磁共振扩散峰度成像对腰椎间盘退变的诊断价值[J].磁共振成像,2018,9(2):113-116,4.基金项目
医学信息分析及肿瘤诊疗湖北省重点实验室开放课题基金项目(编号:PJS140011511) This work was part of Hubei Key Laboratory of Medical Information Analysis and Tumor Diagnosis& （编号:PJS140011511）
Treatment(No.PJS140011511). （No.PJS140011511）
