重庆医学2018，Vol.47Issue(3)：365-367,370,4.DOI:10.3969/j.issn.1671-8348.2018.03.024
36例复发胶质母细胞瘤再治疗患者临床资料分析
Analysis on clinical data in 36 cases of recurrent glioblastoma retreatment
张溢华 1王昊 1曾实 1欧阳庆 1贺绪智 1易良 1许民辉 1徐伦山1
作者信息
- 1. 第三军医大学大坪医院野战外科研究所神经外科,重庆400042
- 折叠
摘要
Abstract
Objective To study the factors influencing prognosis in the patients with recurrent glioblastoma muhiforme (GBM) and to investigate the effect of retreatemt.Methods The retrospective analysis method was adopted to collect the clinical and follow up data in 36 cases of recurrent GBM retreatment in the neurosurgery department of this hospital from March 2008 to March 2013.The prognosis influencing factors were analyzed.Results The univariate analysis results showed that the gender,resection degree,treatment mode and initial scheme had the influence on the progression free survival(P＜0.05).The resection degree had an impact on the overall survival(P＜0.05).The multivariate analysis results showed that KPS score,resection degree and treatment mode had effect on the progression free survival(P＜0.05).The resection degree had an influence on the overall survival (P＜0.05).Conclusion If the patients with recurrent GBM still hasthe chance of operation whole excision,the re-treatment can reach the effect for relieving the symptoms,improving the quality of life and prolonging the survival period.关键词
胶质母细胞瘤/复发/再手术/综合疗法Key words
glioblastoma/recurrence/reoperation/combined modality therapy分类
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张溢华,王昊,曾实,欧阳庆,贺绪智,易良,许民辉,徐伦山..36例复发胶质母细胞瘤再治疗患者临床资料分析[J].重庆医学,2018,47(3):365-367,370,4.
