儿科药学杂志2018，Vol.24Issue(2)：30-32,3.DOI:10.13407/j.cnki.jpp.1672-108X.2018.02.010
布地奈德联合复方异丙托溴铵雾化吸入治疗毛细支气管炎的疗效
Atomize Inhaling Budesonide Combined with Compound Ipratropium Bromide on Bronchiolitis
王永芳 1王爱平 1王璇 1许玉芳1
作者信息
- 1. 郑州市第一人民医院,河南郑州450004
- 折叠
摘要
Abstract
Objective:To observe the therapeutic effect of atomize inhaling budesonide and compound ipratropium bromide in bronchiolitis and explore the prognostic influence of budesonide.Methods:One hundred and twelve children with bronchiolitis were divided into 3 groups randomly.The children in group 1 were treated 7 days with budesonide and compound ipratropium bromide,continued to therapy with budesonide 3 months,the children in group 2 were treated 7 days with budesonide and salbutamol,and the control group was treated 7 days with salbutamol only.The disappearance time of the symptoms and the hospital stay were observed and therapeutic effects in 3 groups were evaluated.The number and rate of asthmatic disease were followed up 1 year after discontinuation of the treatment.Results:The disappearance time of the symptoms and the hospital stay in treatment group were shorter than those in the control group (P＜0.05),and the group 1 were shorter than group 2.The effect rate of the group 1 was higher than group 2 and the control group(P＜0.01).With 1 year treatment in asthmatic disease,the prevalence rate in treatment group 1 (25.0％) was lower than group 2 (48.5％) and control group (51.4％) (P＜0.05),but there was no statistical significance in group 2 and the control group (P＞0.05).Conclusion:The therapeutic effect of atomize inhaling budesonide and compound ipratropium bromide to reduce the acute symptoms of children with bronchiolitis is sure.It can reduce the risk to develop asthmatic disease with inhaled budesonide as an early intervention.关键词
布地奈德/复方异丙托溴铵/毛细支气管炎/预后Key words
budesonide/compound ipratropium bromide/bronchiolitis/prognostics分类
医药卫生引用本文复制引用
王永芳,王爱平,王璇,许玉芳..布地奈德联合复方异丙托溴铵雾化吸入治疗毛细支气管炎的疗效[J].儿科药学杂志,2018,24(2):30-32,3.
