儿科药学杂志2018,Vol.24Issue(2):41-43,3.DOI:10.13407/j.cnki.jpp.1672-108X.2018.02.014
首发儿童青少年精神分裂症患者临床用药分析与比较
Clinical Drug Use in Children and Adolescent with First-Episode Schizophrenia
林红1
作者信息
- 1. 宜昌市精神卫生中心,三峡大学精神卫生研究所,湖北宜昌443005
- 折叠
摘要
Abstract
Objective:To investigate the clinical drug use and efficacy of the first-episode children and adolescents schizophrenia.Methods:The clinical data,efficacy and adverse reactions of hospitalized patients of 96 first-episode children and adolescent (children group) with schizophrenia were retrospectively from 2015 to 2016,and compared with those of 98 adults cases (adults group).Results:The two groups of patients were mainly treated with a single medication and the second generation antipsychotic drugs.There were no significant differences between the doses of antipsychotic drugs.The adverse effects of extrapyramidal side effect and prolactin levels in the children group were significantly higher than those in the adult group,and patients with combined use of diphenhydramine or propranolol were significantly more than those in the adult.Conclusion:The first episode of schizophrenia in children and adolescents is more sensitive to adverse reactions,it is recommended to single use the second generation antipsychotic drugs,and can be treated with modified electric convulsive therapy when invalid.关键词
儿童/青少年/精神分裂症/用药分析Key words
children/adolescents/schizophrenia/clinical drug analysis分类
医药卫生引用本文复制引用
林红..首发儿童青少年精神分裂症患者临床用药分析与比较[J].儿科药学杂志,2018,24(2):41-43,3.