广东医学2018，Vol.39Issue(1)：13-16,4.
地佐辛联合地塞米松预先给药对宫腔镜手术患者苏醒质量及术后镇痛效果的影响
Effect of pretreatment of Dezocine combined with dexamethasone on analgesia and recovery quality for hysteros-copy
修欢欢 1张涛 1李颖源 1许逸欣 1赵悦 1徐康清1
作者信息
- 1. 中山大学附属第一医院麻醉科,广东广州510080
- 折叠
摘要
Abstract
Objective To investigate the analgesic and sedative effects of pretreatment of dezocine in combination with dexamethasone in patients with hysteroscopy.Methods A total of 120 patients with selective hysteroscopy(ASA I-II,aged 29-50 years)were randomly assigned to 3 groups.All patients were given with intravenous propofol by 3 mg/kg · min in the induction of anesthesia.Group A additionally received an intravenous injection of dezocine(0.1 mg/kg)and dexamethasone(10 mg)15 min before operation.Group B was further given with dezocine(0.1 mg/kg).Group C re-ceived intravenous saline as placebo.The time for falling asleep,the operation time,the recovery time(from the end of surgery to opening eyes upon callings),the time of shaking hands under instructions,the total amounts of propofol and re-spiratory inhibition(SpO2<93%or apnea>15 s),and postoperative adverse reaction(e.g.nausea and vomiting)were recorded.Postoperative uterine contraction pain and visual simulation score(VAS)were also evaluated.Results There was no significant difference in the time for falling asleep or the operation time among the three groups(P<0.05).The dosage of propofol and the incidence of respiratory inhibition were significantly lower in Group B than Group C(P <0.05).The recovery time and directional force recovery were significantly shorter in Group B than Group C(P<0.05). The VAS scores 2 and 4 hours after operation in Group B were significantly less than Group C(P<0.05).The VAS scores 8,12 and 24 hours after operation and the incidences of nausea and vomiting in Group A were significantly lower than Group B(P<0.05).Conclusion The combined application of dezocine and dexamethasone before hysteroscopic surgery can effectively relieve postoperative pain,shorten recovery time, reduce adverse reactions, and improve compre-hensive satisfaction.关键词
静脉麻醉/预防性镇痛/地佐辛/丙泊酚/地塞米松Key words
intravenous anesthesia/Preventive analgesia/Dezocine/Propofol/Dexamethasone引用本文复制引用
修欢欢,张涛,李颖源,许逸欣,赵悦,徐康清..地佐辛联合地塞米松预先给药对宫腔镜手术患者苏醒质量及术后镇痛效果的影响[J].广东医学,2018,39(1):13-16,4.
