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非HPV感染相关宫颈腺癌的研究进展

王遥

国际妇产科学杂志2018,Vol.45Issue(1):60-65,6.
国际妇产科学杂志2018,Vol.45Issue(1):60-65,6.

非HPV感染相关宫颈腺癌的研究进展

Review of HPV-Negative Adenocarcinoma of the Uterine Cervix

王遥1

作者信息

  • 1. 100730北京,中国医学科学院北京协和医学院北京协和医院妇产科
  • 折叠

摘要

Abstract

High-risk human papillomavirus(hrHPV)infection is the main cause of cervical intraepithelial neoplasia and invasive cervical cancer and closely related with the occurrence of cervical squamous cell carcinoma and most cervical adenocarcinoma.However,researchers have found that cervical cancer with negative hrHPV test results still exists,and about 10% of the carcinogenesis of cervical adenocarcinoma has no relationship with HPV infection. These adenocarcinoma mainly include: minimal deviation adenocarcinoma which belongs to gastric-type mucinous adenocarcinoma, clear cell carcinoma, mesonephric adenocarcinoma and papillary serous carcinoma. These unusual types of cervical adenocarcinoma were often misdiagnosed due to lack of specific clinical manifestations and difficulty in screening and diagnosis, so that most patients missed the best time of treatment and the prognosis was poor. This review summarizes the advances in the etiology, clinical manifestations, diagnosis, treatment and prognosis of cervical cancer associated with non-HPV infection by reviewing the literature.

关键词

腺癌/宫颈肿瘤/诊断/治疗/预后

Key words

Adenocarcinoma/Uterine cervical neoplasms/Diagnosis/Therapy/Prognosis

引用本文复制引用

王遥..非HPV感染相关宫颈腺癌的研究进展[J].国际妇产科学杂志,2018,45(1):60-65,6.

国际妇产科学杂志

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1674-1870

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