中医药导报2018，Vol.24Issue(2)：50-52,62,4.
楝栀口服液质量标准研究
Study on the Quality Standard of Lianzhi Oral Liquid（楝栀口服液）
黎军 1覃子龙 1李隽永1
作者信息
- 1. 广西柳州食品药品检验所,广西柳州545006
- 折叠
摘要
Abstract
Objective:To establish a method for quality standard of Lianzhi oral solution.Method:The berberine hydrochloride of Coptis chinensis and the tetrahydropalmatine of corydalis tuber in this medicine were identified qualitatively by TLC and the contents of geniposide and paeoniflorin in Lianzhi oral solution were determined simultaneously by HPLC,the separation was performed on Waters SunFire C18 column with mobile phase consisted of acetonitrile-0.2％ phosphoric acid solution (15:85) at the flow rate of 1.0 mL/min.The detection wavelength was set at 238 nm and injection volume was 10 μL.Results:The linear range was 0.0041-0.4000 μg for geniposide,0.0041-0.4064 μg for paeoniflorin,and the average recoveries of them were 98.13％ (RSD％=1.11％,n=6),97.27％(RSD％=1.45％,n=6),respectively.The author established the identification and content determination method of Lianzhi oral solution.Conclusion:The method is simple,accurate and repeatability,and offers scientific and feasible basis for control the quality of Lianzhi oral solution.关键词
楝栀口服液/质量标准/薄层色谱/盐酸小檗碱/延胡索乙素/高效液相色谱法/栀子苷/芍药苷Key words
Lianzhi oral solution/quality standard/TLC/berberine hydrochloride/tetrahydropalmatine/HPLC/geniposide/paeoniflorin分类
医药卫生引用本文复制引用
黎军,覃子龙,李隽永..楝栀口服液质量标准研究[J].中医药导报,2018,24(2):50-52,62,4.
