检验医学与临床2018，Vol.15Issue(4)：469-471,3.DOI:10.3969/j.issn.1672-9455.2018.04.012
自贡地区妊娠期甲状腺功能血清指标生物参考区间
Biological reference interval of serum thyroid function during pregnancy in Zigong area
摘要
Abstract
Objective To establish the biological reference interval of serum thyroid function during preg-nancy in Zigong area.Methods Based on the standard of NACB,combined with the pregnancy result,568 ca-ses of normal pregnant women and 186 cases of non pregnant women were selected.Thyroid peroxidase anti-body(TPOAb),thyrotropin(TSH)and free thyroxine(FT4) were detected respectively.Results The preg-nancy data didn′t match normal distribution.TSH decreased in the T1 phase,got the rock bottom in 8―12 weeks and then gradually increased.FT4 increased in the T1 phase and then decreased,significantly in 18―26 weeks.Conclusion:In Zigong area,the TSH biological reference interval as follows:0.06-4.37 mIU/L in T1 stage,0.27-4.20 mIU/L in T2 stage,0.65-5.73 mIU/L in T3 stage;the FT4 biological reference interval as follow s:6.51-13.06 pmol/L in T1 stage,4.25-10.54 pmol/L in T2 stage,3.86-9.13 pmol/L in T3 stage. Conclusion There are certain differences in TSH and FT4 biological reference interval during pregnancy in Zigong area compared with other areas in China.To establish corresponding detection system of biological ref-erence interval of thyroid function during pregnancy helps to improve the ability of treatment of thyroid dis-ease during pregnancy.关键词
妊娠/甲状腺功能/生物参考区间Key words
pregnancy/thyroid function/biological reference interval分类
医药卫生引用本文复制引用
徐梅,韦懿..自贡地区妊娠期甲状腺功能血清指标生物参考区间[J].检验医学与临床,2018,15(4):469-471,3.基金项目
四川省自贡市重点科技计划任务项目(2016ZC51). （2016ZC51）
