检验医学与临床2018，Vol.15Issue(4)：482-484,3.DOI:10.3969/j.issn.1672-9455.2018.04.016
射频消融术联合索拉菲尼靶向治疗对晚期肝癌患者的疗效研究
Efficacy of radiofrequency ablation combined with Sola Feeney targeted therapy in patients with advanced liver cancer
向爱生 1魏瑞1
作者信息
- 1. 中南大学湘雅医院肿瘤科,长沙410008
- 折叠
摘要
Abstract
Objective To investigate the effect of radiofrequency ablation combined with Sola Feeney targe-ted therapy on quality of life and long-term survival in patients with advanced liver cancer.Methods A total of 78 patients with advanced liver cancer treated in our hospital from June 2011 to June 2014 were divided into observation group 39 cases and control group 39 cases according to the random number table method.The ob-servation group was treated with radiofrequency ablation combined with Sola Feeney targeted therapy,while the control group was only treated with Sola Feeney targeted therapy.The DCR rate was compared between the two groups before and after treatment.The immune function and quality of life were improved,and the survival rates of the patients were followed up for 1 and 2 years.Results The observation group DCR (69.23% )was higher than that of the control group(48.72% )(P<0.05);the observation group after treat-ment CD3+,CD4+,CD4+/CD8+were higher than those of the control group(P<0.05);the observation group after treatment,social function,emotional function,physical function,cognitive function and role function score were higher than those of those of the control group(P<0.05);the observation group 1 years survival rate (66.67% )and 2 year survival rate(53.85% )were higher than those of the control group 1 years survival rate (46.15% )and 2 year survival rate(30.77% )(P<0.05).Conclusion Radiofrequency ablation combined with Sola Feeney targeted therapy can improve the quality of life and prolong the survival time of advanced liver cancer.关键词
射频消融术/索拉菲尼/肝癌,晚期Key words
radiofrequency ablation/Sola Feeney/advanced liver cancer分类
医药卫生引用本文复制引用
向爱生,魏瑞..射频消融术联合索拉菲尼靶向治疗对晚期肝癌患者的疗效研究[J].检验医学与临床,2018,15(4):482-484,3.
