摘要
Abstract
Objective To evaluate the value of esophageal endoscopic ultrasound-guided fine needle aspira-tion(EUS-FNA) combing with immunocytochemistry (IHC) in patients with solid mediastinal lesions. Methods A total of 83 patients with solid mediastinal lesions were diagnosised by EUS-FNA consecutively, the results of cytology,histology and immunohistochemistry were analyzed retrospectively.Results A total of 79 patients(95.2% ) were diagnosed by EUS-FNA finally,including malignant tumor 72 cases and benign tumor/tuberculosis 7 cases.The sensitivity,specificity,accuracy,positive predictive value,negative predictive value for EUS-FNA of mediastinal malignant tumor in patients were 94.7%,100.0%,95.2%,100.0%, 63.6%,respectively.39 cases(49.4% )were diagnosed by immunohistochemistry,of which 32 were lung canc-er,accounting for 50.8% (32/63)of all lung cancer.Conclusion EUS-FNA joint immunohistochemical can im-prove the accuracy of the diagnosis in solid mediastinal lesions,especially for precision classification in lung cancer with mediastinal metastasis.关键词
纵隔实性病变/超声内镜细针活检/免疫组化/肺癌Key words
solid mediastinal lesions/EUS-FNA/immunohistochemistry/lung cancer分类
临床医学
