检验医学与临床2018，Vol.15Issue(4)：513-516,4.DOI:10.3969/j.issn.1672-9455.2018.04.025
左心室肥厚对慢性阻塞性肺疾病急性加重期住院结果的研究
Influence of left ventricular hypertrophy on in-hospital outcomes in acute exacerbation of chronic obstructive pulmonary disease
摘要
Abstract
Objective To explore correlation between left ventricular hypertrophy(LVH)and clinical out-comes in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods During January 2015 to December 2016 at department of pulmonary,61 cases with AECOPD with a-vailable echocardiographic data were included.LVH was defined as LV mass index(LVMI) > 120 g/m2 (women)and >125 g/m2(men).Wall thickness was used to classify LVH as concentric(>0.42)or eccentric (<0.42).Outcomes included need for and duration of non-invasive ventilation(NIV)and mechan-ical ventila-tion(MV),intensive care unit(ICU) and total length of stay.Results Of 61 patients with AECOPD,32 (52.5% )patients having LVH and 29(47.5% )were included.There were no statistically significant in NIV and MV use and duration,ICU and total duration between LVH and non-LVH cohort.Of the 32 LVH patients had 19(59.4% )concentric LVH and 13(40.6% )eccentric LVH.Concentric LVH was predictive of greater NIV use [10(52.6% ) vs.2(15.4% ),P<0.01]and duration[(1.0 ± 1.9) vs.(0.6 ± 1.4)days,P<0.01]com-pared to eccentric LVH.Concentric LVH remained independently associated with NIV duration(P=0.009). Conclusion In-hospital outcomes in patients with AECOPD were comparable in patients with and without LVH.Patients with concentric LVH had higher NIV need and duration in comparison to eccentric LVH.关键词
慢性阻塞性肺疾病急性加重期/左心室肥厚/左心室质量指数/向心性肥厚/无创通气Key words
acute exacerbation of chronic obstructive pulmonary disease/left ventricular hypertrophy/left ventricular mass index/concentric hypertrophy/non-invasive ventilation分类
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张凌波,谢媛媛,翟福利,蔡晓聪..左心室肥厚对慢性阻塞性肺疾病急性加重期住院结果的研究[J].检验医学与临床,2018,15(4):513-516,4.
