临床误诊误治2018，Vol.31Issue(2)：102-106,5.DOI:10.3969/j.issn.1002-3429.2018.02.028
不同时长吸氧治疗对精神分裂症患者无抽搐电休克治疗后短时记忆的影响
Effect of Different Duration of Oxygen Therapy on Short-term Memory in Patients with Schizophrenia after Modified Electroconvulsive Therapy
摘要
Abstract
Objective To invstigate effect of different duration of oxygen therapy on short-term memory(STM) in pa-tients with schizophrenia after modified electroconvulsive therapy (MECT). Methods A total of 160 patients with schizo-phrenia were divided into control group (n=40),experiment group 1 (n=40), experiment group 2 (n= 40) and experi-ment group 3 (n= 40). All the patients received MECT. After MECT,experiment group 1,2 and 3 received oxygen therapy for 20 min,40 min,and 60 min respectively,while control group did not received oxygen therapy. Positive and negative syn-drome scale(PANSS) scores before and at 24h and in 4 weeks after treatment,and memory quotient(MQ) values before and at 24 h and in 1,2 and 4 weeks after treatment were observed and compared in four groups. Results There were significant differences in PANSS scores at different times in each group (P<0.05). Compared with those before treatment in the same group,PANSS scores at 24h and in 4 weeks after treatment were significantly lower in each group,and the PANSS score in 4 weeks after treatment was significantly lower than that at 24h after treatment in the same group(P<0.05). There were signif-icant differences in MQ values at different times in each group(P<0.05). Compared with that before treatment in the same group,MQ value at 24h after treatment was significantly lower in each group(P<0.05). Compared with those at 24 h after treatment,MQ value was significantly increasing in 2 weeks after treatment in control group,while the value was significantly increasing in 1 week after treatment in experiment group 1(P<0.05). In experiment group 2,MQ value was significantly in-creasing in 1 week after treatment compared with that at 24h after treatment, and the values in 1,2 and 4 weeks after treat-ment were significantly increased compared with those before treatment(P<0.05). In experiment group 3,MQ value was in-creasing in 1 week after treatment compared with that at 24h after treatment, and the value was significantly increased at 2 weeks after treatment compared with those before treatment(P<0.05). There were significant differences in MQ values in 1, 2 and 4 weeks after treatment in each group (P<0.05),and the MQ values in experiment group 2 were significantly higher than those in control group and experiment group 1(P<0.05). Conclusion A continuous oxygen inhalation for 40 min may effectively improve STM dysfunction after MECT in patients with schizophrenia.关键词
精神分裂症/电休克/氧吸入疗法/记忆,短时Key words
Schizophrenia/Electroshock/Oxygen inhalation therapy/Memory,short-term分类
医药卫生引用本文复制引用
张国玲,于滨,张红,高淑英..不同时长吸氧治疗对精神分裂症患者无抽搐电休克治疗后短时记忆的影响[J].临床误诊误治,2018,31(2):102-106,5.基金项目
北京市科学技术委员会首都临床特色应用研究项目(Z141107002514039) （Z141107002514039）
