环境与职业医学2018，Vol.35Issue(1)：19-23,5.DOI:10.13213/j.cnki.jeom.2018.17500
宁波市6种大气污染物暴露与孕妇早产关系的时间序列分析
A time-series analysis on association between exposure to six air pollutants and preterm birth in Ningbo
摘要
Abstract
[Objective] To analyze the effects of exposure to six air pollutants [fine particulate matters (PM2.5),coarse particulate matters (PM10),sulfur dioxide (SO2),nitrogen dioxide (NO2),carbon monoxide (CO),and ozone (O3)] on preterm birth in Ningbo.[Methods] A generalized linear distributed lag model for time-series data was adopted.The effects of the concentrations of six air pollutants on preterm birth from January 2014 to December 2015 in Ningbo were assessed after controlling confounding factors such as long-term trends,meteorological factors,and day of the week.[Results] Significant lag effects of PM2.5,SO2,NO2 (each 10μg/m3 increase),and CO (each 0.1 mg/m3 increase) were identified on preterm birth,with RR (95％CI) of 1.015 (1.000-1.032) for PM2.5 on lag1;1.073 (1.016-1.133),1.053 (1.000-1.109),1.060 (1.009-1.115),and 1.062 (1.010-1.116) for SO2 on lag0,lag2,lag3,and lag4;1.031 (1.005-1.058) and 1.027 (1.002-1.054) for NO2 on lag0 and lag1;and 1.350 (1.079-1.688) for CO on lag3,respectively.Significant accumulative effects were only shown for SO2 on preterm birth,with RR(95％CI) of 1.099(1.019-1.186) and 1.091 (1.001-1.189) for average 1 week and 2 weeks of accumulation.[Conclusion] Exposure to air pollutants may contribute to the risk of preterm birth,showing both lag effects and accumulative effects.关键词
空气污染/PM2.5/早产/滞后效应/累积效应Key words
air pollution/PM2.5/preterm birth/lag effect/accumulative effect分类
医药卫生引用本文复制引用
刘文渊,施丹华,吴军华,徐亚男,卢文波,邱海燕..宁波市6种大气污染物暴露与孕妇早产关系的时间序列分析[J].环境与职业医学,2018,35(1):19-23,5.基金项目
浙江省人口计划生育科研项目(编号:2014KYB356,2014KYA273) （编号:2014KYB356,2014KYA273）
宁波市科技局科技创新团队项目(编号:2014B82003) （编号:2014B82003）
宁波市母胎医学研究重点实验室项目(编号:2010A22011) （编号:2010A22011）
