山西医科大学学报2018，Vol.49Issue(1)：36-39,4.DOI:10.13753/j.issn.1007-6611.2018.01.008
循环C1q/TNF相关蛋白1的水平与男性冠心病的关系
Relationship between loop C1q/tumor necrosis factor related protein 1 and coronary heart disease in male
钟节雄 1杨宏华2
作者信息
- 1. 武汉商职医院心血管内科,武汉430000
- 2. 武汉大学人民医院儿科
- 折叠
摘要
Abstract
Objective To investigate the correlation between circulating C 1q/tumor necrosis factor-related protein (CTRP) 1 level in blood and prevalence of coronary heart disease(CHD) in male.Methods A total of 81 male patients with CHD and 55 male healthy controls at the same time were selected in this study.The baseline data were collected,and the levels of blood lipid,fasting blood glucose(FBG) and CTRP1 were measured.Results Compared with healthy controls,the body mass index(BMI),systolic blood pressure,FBG,blood lipid levels (TC and LDL-C) and CTRP1 were significantly increased in CHD patients,while adiponectin was significantly decreased(P ＜0.05).Plasma CTRP1 levels were positively correlated with BMI,systolic blood pressure,FBG and serum lipids(TC and LDL-C) and negatively correlated with adiponectin (all P ＜ 0.05).Logistic regression analysis displayed that CTRP1 was a risk factor for CHD (OR =1.347,P ＜ 0.05).Conclusion Increased circulating plasma CTRP1 might be used as a new biological marker for male CHD,which has a certain value to assess the risk of male cardiovascular diseases.关键词
男性/冠心病/CTRP1/风险因子Key words
male/coronary heart disease/CTRP1/risk factors分类
医药卫生引用本文复制引用
钟节雄,杨宏华..循环C1q/TNF相关蛋白1的水平与男性冠心病的关系[J].山西医科大学学报,2018,49(1):36-39,4.
